Asymmetric dimethylarginine: a risk indicator or pathogenic factor?
نویسندگان
چکیده
منابع مشابه
Asymmetric Dimethylarginine (adma): a Mediator of Endothelial Dysfunction and a Novel Cardiovascular Risk Factor
Asymmetric dimethylarginine (ADMA) is involved in the pathogenesis of hypertension and atherosclerosis by inhibiting the generation of nitric oxide, an endogenous vasculoprotective molecule. Determination of ADMA helps to predict a patient`s probability of experiencing death or cardiovascular disease. A novel competitive ADMA-ELISA that has recently been developed and validated by us is a usefu...
متن کاملAsymmetric dimethylarginine, race, and mortality in hemodialysis patients.
BACKGROUND AND OBJECTIVES Levels of asymmetric dimethylarginine, an inhibitor of nitric oxide synthase, are elevated in kidney disease and associated with mortality in white European hemodialysis populations. Nitric oxide production and degradation are partially genetically determined and differ by racial background. No studies have measured asymmetric dimethylarginine in African Americans on d...
متن کاملAsymmetric dimethylarginine (ADMA) a novel cardiovascular risk factor--evidence from epidemiological and prospective clinical trials.
There is a growing clinical evidence to support the hypothesis that asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase is a new independent cardiovascular risk factor. ADMA mediates endothelial dysfunction in lipid disorders, coronary artery disease, chronic heart failure, diabetes mellitus and hypertension. The aim of this review was to summarize the latest ev...
متن کاملRole in Hypercholesterolemia Asymmetric Dimethylarginine (ADMA): A Novel Risk Factor for Endothelial Dysfunction
Rainer H. Böger, Stefanie M. Bode-Böger, Andrzej Szuba, Philip S. Tsao, Jason R. Chan, : Its Role in Hypercholesterolemia Asymmetric Dimethylarginine (ADMA): A Novel Risk Factor for Endothelial Dysfunction Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 1998 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Da...
متن کاملThe Study of Serum Asymmetric Dimethylarginine Concentrations in the Different Paraoxonase Phenotypes of Exudative Age-related Macular Degeneration Disease
Background and Aims: Age-related macular degeneration (ARMD) is a degenerative retinal disorder that causes progressive loss of central vision in older adults. The study aimed to determine the effect of asymmetric dimethylarginine (ADMA) as oxidizing metabolite and paraoxonase (PON1) activity within its phenotypes as an antioxidant agent in the development of such multifactorial disease. Mater...
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عنوان ژورنال:
- Polskie Archiwum Medycyny Wewnetrznej
دوره 126 9 شماره
صفحات -
تاریخ انتشار 2016